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Letybo (letibotulinumtoxinA-wlbg) is a botulinum toxin type A injectable for wrinkle relaxation, in the same drug class as Botox and Dysport. The FDA approved it in February 2024 for the temporary improvement of moderate to severe glabellar lines, the vertical lines between the brows that show up when you frown, squint, or concentrate.
Letybo is manufactured by Hugel, Inc., a South Korean pharmaceutical company that had already been selling botulinum toxin products in Asian and European markets before Letybo reached FDA approval in the US. At New Day Medspa, it's injected by licensed, medically trained aesthetic providers who treat frown lines every day and know how to dose for a result that reads as rested, not done.
Softens moderate to severe frown lines between the brows
FDA-approved formula backed by clinical trial data
Preserves natural expression, no frozen look
Noticeable softening in as little as 2 to 3 days
Results last 16 weeks on average
Administered by licensed ARNPs and PAs in Jacksonville, FL
Letybo blocks the nerve signals that tell your corrugator and procerus muscles, the small muscles between your brows, to contract. Less muscle movement means the skin above it stops folding into a crease every time you frown.
Letybo's FDA approval was supported by clinical trials involving more than 1,270 patients. Across those trials, patients generally saw noticeable softening within 2 to 3 days, with full effect settling in over the following 2 to 4 weeks. Results typically lasted 16 weeks. Letybo shouldn't be re-injected more often than every 3 months, which lines up with how long most patients see it last anyway.
Letybo is a more budget friendly alternative to other wrinkle relaxer brands, with pricing as low as $9.99 per unit. It is now New Day Medspa's most popular wrinkle relaxer option.

Frown Lines (Glabella/"11s")
Forehead Lines
Crow's Feet
Bunny Lines (scrunch lines on nose)
Lip Flip
Brow Lift
Gummy Smile
Chin Smoothing
Neck Bands
Your provider assesses how your forehead and brow muscles move, discusses your goals, and maps out a dose. This isn't a one-size treatment; your dose depends on your muscle strength and how deep your lines are.
No downtime. You can go back to your day right away. Your provider will give you a short list of things to skip for 24 hours, like lying flat or rubbing the treated area, to keep the product where it's supposed to be.
Early softening can show up within 2 to 3 days. Full results typically settle in over the following 2 to 4 weeks.


*Results may vary
How long does Letybo last?
Results typically last up to 16 weeks for most patients, based on the clinical trial data submitted to the FDA. Individual results vary by dose, muscle strength, and metabolism.
Will I look frozen?
That's not the goal, and it's not how Letybo is dosed at New Day Medspa. The aim is softer lines with your expression still intact.
Is Letybo the same as Botox?
They're both botulinum toxin type A products and work the same way, but they're different formulations from different manufacturers. Letybo's FDA approval is specific to glabellar lines. Your provider can walk you through how the two compare if you're switching from one to the other.
Does Letybo hurt?
Most patients describe it as a series of quick pinches. The injections themselves take a few minutes.
Can I combine Letybo with other treatments?
Most clients describe the sensation as a quick pinch. We use ultra-fine aesthetic syringes and offer topical numbing if needed.
Book a free consultation with New Day Medspa in Jacksonville, FL, and find out if Letybo is the right fit for you.
